Sugary Drinks and Stomach Cancer; GLP-1 Use in IBD; Fiber Supplements for IBS

Prospective data from the U.S. found that people who drank a sugar-sweetened beverage each day had a more than twofold risk of developing gastric cancer. (Gastro Hep Advances)

A randomized trial failed to support the routine administration of preoperative high-dose corticosteroids as a means of preventing severe complications or improving recovery after elective digestive cancer surgeries. (JAMA Surgery)

With nearly 15 years of follow-up, findings from a prospective cohort study showed that colorectal cancer (CRC) mortality was 26% lower for participants who received an invitation for fecal occult screening. (JAMA Network Open)

U.S. declines in CRC mortality from 2000 to 2019 happened across all races and ethnicities, though rates remained stubbornly high in certain areas and populations. (JAMA Oncology)

A WhatsApp chatbot scored a win over standard text messaging for boosting CRC screening uptake in a Hong Kong study. (Clinical Gastroenterology and Hepatology)

Claims data suggested a similar 3-year cancer risk among inflammatory bowel disease (IBD) patients on advanced therapies, ranging from 2% with anti-interleukin drugs to 2.7% with vedolizumab (Entyvio). (Clinical Gastroenterology and Hepatology)

Experts in Inflammatory Bowel Diseases reviewed the use of GLP-1 agonists in IBD.

Use of hormonal contraception in women with ulcerative colitis was not associated with an increased risk of disease flare-ups, according to a retrospective study. (Inflammatory Bowel Diseases)

Fiber supplements can increase clinical responses in irritable bowel syndrome (IBS), a meta-analysis of randomized trials indicated, with psyllium called out as being of particular benefit. (Gastroenterology)

A population-based internet survey in Gut reported that Rome V criteria turned up a similar global prevalence of disorders of gut-brain interaction (DGBI) in adults compared with Rome IV criteria (40.9% vs 40.5%).

And in kids, a multinational study using Rome V criteria showed a DGBI prevalence of 28%, including 30% in the U.S. (Gut)

Roughly one in 70 people worldwide are seropositive for celiac disease, according to a systematic review and meta-analysis. (Gastroenterology)

New CDC stats showed alcohol-induced deaths increasing from 2014 to 2024, with a sharp pandemic spike. (Morbidity and Mortality Weekly Report)

A rotational thromboelastometry-guided algorithm during invasive procedures for adults with cirrhosis could reduce blood transfusions without increasing bleeding risks, according to a small randomized trial. (Clinical Gastroenterology and Hepatology)

And in autoimmune hepatitis, a case series suggested some potential for rituximab in tough-to-treat patients. (Gastro Hep Advances)