Early Sugar Exposure and Cancer Risk; Melanoma Vaccine Win; ‘Antifreeze’ for CAR-T

People who had restricted sugar exposure during the first 2 years of life grew into adults with a lower risk of cancer. (American Journal of Clinical Nutrition)

Meanwhile, women who consumed a diet high in antioxidants had a lower risk of cervical cancer. (International Journal of Gynecology & Obstetrics)

The FDA declined to approve Xspray Pharma’s investigational formulation of dasatinib for chronic myeloid leukemia and acute lymphoblastic leukemia due to manufacturing issues, the company said.

Major League Baseball player Trey Mancini, 34, announced his retirement from a career that included a Comeback Player of the Year award after taking a year off to get treatment for colon cancer. (ESPN)

Adding the cancer vaccine intismeran autogene to pembrolizumab (Keytruda) significantly improved recurrence-free survival and distant metastasis-free survival in a phase III trial of completely resected melanoma, Merck and Moderna announced.

The novel, first-in-class antibody-drug conjugate izalontamab brengitecan improved progression-free survival versus chemotherapy in progressive EGFR-mutated lung cancer. (Fierce Pharma)

Fewer than 15% of people eligible for lung cancer screening with low-dose CT have actually discussed screening with their doctors. (University of Cincinnati)

People who live to 100 or older have an abundance of cancer-fighting immune cells. (Cell Reports)

A cell-preservation technique that uses naturally occurring sugars as “antifreeze” could help make CAR T-cell therapy more widely available. (MIT News)

Personalized obesity treatment that includes weight-loss medications may improve the long-term health of breast cancer survivors. (John Hopkins Medicine)

A study of lung cancer patients showed that obesity weakened the body’s cancer-fighting immune activity, but physical activity might help reverse that effect. (Roswell Park Comprehensive Cancer Center)

Five-year survivors of Hodgkin lymphoma still have an increased risk of earlier death from non-cancer conditions, particularly cardiovascular disease. (University of Texas MD Anderson Cancer Center)

A comparison of government- and pharma-funded clinical trials in oncology showed distinctly different trial designs and objectives. (SWOG Cancer Research Network)

In a decision that could have far-reaching implications, a federal appeals court agreed with a lower court that alternative funding programs, a growing business to counter high prices of prescription drugs, may not import Gilead drugs from overseas for resale in the U.S. (CNBC)

Snopes examined the claims and facts surrounding President Trump aide Natalie Harp’s comments on how the “right-to-try” law helped her survive a rare bone cancer.