Ultrasounds for Schizophrenia; ‘Circadian’ Depression; GLP-1s and Eating Disorders

A single, 10-minute transcranial ultrasound session led to a modest but significant drop in delusion scores among people with schizophrenia in a sham-controlled pilot trial. (npj Acoustics)

President Trump announced that the firing squad execution of Fort Hood shooter and former Army psychiatrist Nidal Hasan, MD, will not be livestreamed. (USA Today)

Roughly a quarter of adults with severe, recurrent depressive disorders were found to have a “circadian subtype” of depression, characterized by disrupted 24-hour sleep-wake cycles, according to a cross-sectional study. (British Journal of Psychiatry)

One-third of high school students reported persistent feelings of sadness or hopelessness, with a higher prevalence among females, according to the CDC’s 2025 Youth Risk Behavior Survey.

The same CDC survey showed that 40.5% of high school students reported binge eating on at least 1 day in the past 30 days, with 17.2% reporting 3 or more days.

Few safeguards exist to protect patients with eating disorders amid the GLP-1 drug boom. (New York Times)

In related news, influencer Emilie Kiser opened up about her 7-year battle with an eating disorder. (People)

Rapport Therapeutics announced that a phase II trial of its investigational AMPA receptor negative allosteric modulator met the primary endpoint of reducing acute bipolar mania severity in adults.

The age-standardized suicide mortality rate in the Americas increased by an average of 1.05% annually between 2015 and 2021, primarily driven by increases among males. (Lancet Regional Health Americas)

An Australian qualitative study found that women seeking help for postpartum psychosis often experienced unintentional medical gaslighting. (Journal of Advanced Nursing)

Vanda Pharmaceuticals said it paused development of its experimental social anxiety drug after the compound failed to meet its primary endpoint of reducing distress levels during social stress tests in a phase III study.

What exactly is “purpose anxiety,” and how does it affect mental health? (New York Times)

One in six adults with type 1 diabetes reported moderate to severe depression or anxiety symptoms, according to findings from the National Health Interview Survey. (Annals of Internal Medicine)

Arts-based interventions among children and young people were linked to reduced depression and anxiety, along with improvements in well-being and quality of life, a meta-analysis showed. (eClinicalMedicine)

A former Florida gambling helpline director was sentenced to nearly 10 years in prison for embezzling funds to fuel his own gambling addiction. (The Guardian)