Cancer Deaths Fall, Cases Rise; Diabetes and Cancer Risk; Vitamin C for Cancer

Cancer mortality continued to decline in the U.S. from 2019-2023, driven largely by fewer lung cancer deaths, even as cancer incidence continued to rise, according to the CDC.

A 3D-printed, dissolving microneedle array preloaded with medication passed a proof-of-principle test as a potential transdermal delivery system for chemotherapy. (Advanced Healthcare Materials)

Can bringing clinical trials to patients with cancer, rather than vice versa, increase participation in studies of new therapies and therapeutic strategies that have the potential to improve survival and other outcomes? (ASCO Daily News)

People with type 2 diabetes had double the risk of developing cancer compared with those who did not have diabetes, according to data that will be presented at the upcoming European Association for the Study of Diabetes meeting. (U.S. News & World Report)

A new analysis of a randomized trial showed that up to 87% of patients with relapsed/refractory multiple myeloma treated with teclistamab (Tecvayli) plus daratumumab (Darzalex Faspro) might expect to live as long as an age-matched population without myeloma, Johnson & Johnson announced.

Merck announced FDA approval of belzutifan (Welireg) plus lenvatinib (Lenvima) for previously treated advanced renal cell carcinoma with a clear cell component.

Compass Therapeutics revealed that the FDA wants a survival-focused clinical trial of tovecimig in biliary cancer — which the company considers unnecessary — before submission of a biologics license application for the drug.

Medicare drug price negotiation policies could threaten the financial solvency of many oncology practices by requiring upfront payment for drugs at commercial prices, followed by retrospective reimbursement, according to the Association for Clinical Oncology.

Breast cancer specialists changed their approach to endocrine therapy more than 40% of the time after reviewing results of the Breast Cancer Index, usually in favor of extending endocrine therapy. (JAMA Network Open)

A systematic review showed new insight into stroke secondary to cancer-associated coagulopathy. (Journal of Neurology)

Vitamin C supplements might have a role in preventing myeloid malignancies, such as myelogenous leukemias, in patients who have cancer precursor blood disorders. (Cancer)

National Cancer Institute budget cuts delayed enrollment in a clinical trial of a promising therapy for an aggressive childhood brain cancer, CNBC reported.

Colorectal cancer survivors had less fatigue if they engaged in physical activity, particularly walking, a longitudinal study showed. (Journal of the National Comprehensive Cancer Network)