Keytruda Biosimilar Advances; Oncologist Turned Patient; Will AI Cure Cancer?

Zydus Lifesciences and Formycon AG announced FDA acceptance of a biologics license application for FYB206, a biosimilar to the blockbuster cancer drug pembrolizumab (Keytruda).

The FDA expanded bladder cancer indications for the interleukin-15 receptor agonist nogapendekin alfa inbakicept (Anktiva) to include bacillus Calmette-Guérin-unresponsive non-muscle invasive disease.

Rachna Shroff, MD, a leading clinician and researcher in gastrointestinal (GI) cancers, died earlier this week at age 47 of an undisclosed type of cancer, possibly a GI cancer. (Today)

Clinicians should exercise caution in applying the BI-RADS breast cancer reporting system criteria, developed for adults, to children with breast masses, which are uncommon and usually benign, according to new guidance from the American College of Radiology.

An oncologist who has taken care of patients with breast cancer for 25 years shared what she learned from having the disease. (NBC News)

Delays in breast cancer diagnosis and treatment occurred significantly more often in young women, a cohort study found. (Cancer)

British IndyCar driver Jack Harvey, 33, shared a recent cancer diagnosis on social media without disclosing the type of cancer, but he vowed to be ready for the Indianapolis 500 in May 2027. (People)

U.S. coastal counties with higher levels of marine microplastics pollution had higher rates of several types of cancer, an ecological analysis showed. (University of Hawaii)

The investigational radiopharmaceutical ²²⁵Ac-Dotatate significantly improved progression-free survival (PFS) versus standard care in a phase III trial of patients with previously treated gastroenteropancreatic neuroendocrine tumors, Bristol Myers Squibb announced.

Adding the PSMA-targeted radiopharmaceutical 177Lu-PNT2002 to stereotactic body radiotherapy reduced the risk of progression in recurrent prostate cancer, an updated analysis of the phase II LUNAR trial showed. (UCLA Health)

Merck’s CEO expressed confidence that the production process for the Merck/Moderna breakthrough personalized cancer vaccine will speed up over time. (CNBC)

Meanwhile, BioNTech reported that adding its mRNA cancer vaccine BNT113 to pembrolizumab did not improve PFS in metastatic HPV-positive head and neck cancer.

While Pope Leo’s lung cancer diagnosis and surgery made headlines worldwide, his brother, Louis Prevost, has started treatment for multiple myeloma. (CBS News)

The American Society of Hematology’s new clinical guidance on myelofibrosis includes expanded recommendations for molecular testing, earlier referral for stem cell transplantation, and appropriate use of JAK inhibitors and aspirin.

Convinced that artificial intelligence (AI) will cure cancer, some AI researchers are taking up smoking, according to Palantir’s chief technical officer. (SFist)

An enhanced chimeric antigen receptor (CAR) T-cell therapy showed promise for improving outcomes in a phase I trial of relapsed/refractory B-cell malignancies. (Ohio State University Comprehensive Cancer Center)

Abbott Laboratories said it has recruited retired Major League Baseball star Albert Pujols and current star Cal Raleigh as the pitch men for the “Mind Your Behind” promotion for the Cologuard Plus colon cancer test.