LSD Drug’s Anxiety Win; Alanis Morissette’s ‘Psychosis’; ADHD and GI Issues

Definium Therapeutics’ investigational lysergide (LSD) tablet significantly reduced anxiety in a second phase III trial, meeting the primary and key secondary endpoints, the company announced.

Meanwhile, Contineum Therapeutics and Johnson & Johnson said their investigational selective M1 receptor inhibitor for major depressive disorder failed to meet the primary outcome in a placebo-controlled phase II trial.

A 3-minute interaction with miniature horses and donkeys was associated with improved measures of mood in teens, with greater improvements linked to the ability to read the animals’ body language. (Scientific Reports)

Gov. Maura Healey (D) called for better postpartum care and support in Massachusetts after the Lindsay Clancy trial sparked discussions about unresolved postpartum psychosis. (AP)

Singer Alanis Morissette recently opened up about her struggle with postpartum depression, sharing that she “dipped into psychosis.” (Los Angeles Times via AOL)

What have Health Secretary Robert F. Kennedy Jr. and the Make America Healthy Again movement gotten wrong about selective serotonin reuptake inhibitors? (New York Times)

A large meta-analysis linked attention deficit-hyperactivity disorder (ADHD) to increased odds of several gastrointestinal (GI) issues, including irritable bowel syndrome, constipation, and encopresis. (Journal of Attention Disorders)

Adult-diagnosed ADHD may have a milder clinical and genetic profile than youth-diagnosed cases, a cross-sectional study suggested. (JAMA Network Open)

A six-study meta-analysis showed that stimulant-based pharmacotherapies — specifically higher-dose methylphenidate and mixed amphetamine salts — outperformed placebo in improving both ADHD symptoms and stimulant-use indicators. (Journal of Clinical Psychiatry)

University of Cincinnati researchers are working to increase access to metformin and lifestyle interventions for youth experiencing weight gain from second-generation antipsychotics.

Teva Pharmaceuticals launched an educational website for healthcare providers on long-acting injectable antipsychotics for schizophrenia.

Bonobos founder Andy Dunn discussed his experience with bipolar I disorder, including a week-long psychiatric stay at Bellevue Hospital. (Fortune)

Higher patient panel fullness was associated with increased burnout and intent to leave among Veterans Administration primary care practitioners. (JAMA Network Open)

Tens of thousands of people gathered at a miles-long table in Romania’s capital to set a Guinness record and raise money for what organizers said will be the country’s first pediatric psychiatry hospital. (AP)